¹³¹I-Lipiodol (¹³¹I-Ethiodized Oil) is a generic therapeutic agent which was authorized and available since 1995 under the name Lipiocis® but withdrawn in October 2010 following the observation of lung toxicity. The product came back on the Indian market in 2018 (approval in India, March 2017). The precursor Lipiodol is a mixture of iodinated ethyl esters of fatty acids of poppy seed oil used as a contrast agent for radiology. When labeled with ¹³¹I it is used for the treatment of hepatocarcinoma (HCC) with Portal Vein Thrombosis, non-resectable and untransplantable. ¹³¹I-Lipiodol is also available in Brazil.

Target/Mechanism: Fatty acid containing tissues

Carrier/Ligand: Lipiodol

Radiation type: beta electrons (β^–)